Creatinine Clearance Calculator (Cockcroft-Gault)
This calculator is designed to help medical professionals and patients estimate the creatinine clearance and adjust drug dosages accordingly. It uses the Cockcroft-Gault formula, which requires inputs of age, weight, serum creatinine, and gender.
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Source of Data and Methodology
This calculator uses the Cockcroft-Gault formula, which is widely recognized in clinical practice for estimating creatinine clearance. Read more about the formula. All calculations are based on this trusted source.
The Formula Explained
\[\text{Creatinine Clearance} = \frac{(140 - \text{age}) \times \text{weight} \times \text{factor}}{\text{serum creatinine}}\]
Where the factor is 1.23 for males and 1.04 for females.
Glossary of Variables
- Age: The age of the individual in years.
- Weight: The weight of the individual in kilograms (kg).
- Serum Creatinine: The concentration of creatinine in the blood, measured in milligrams per deciliter (mg/dL).
- Gender: Biological sex which affects the formula factor.
How It Works: A Step-by-Step Example
Consider a 65-year-old male weighing 70 kg with a serum creatinine level of 1.0 mg/dL. Using the Cockcroft-Gault formula, his creatinine clearance is calculated as follows:
\[\text{Creatinine Clearance} = \frac{(140 - 65) \times 70 \times 1.23}{1.0} = 85.05 \, \text{mL/min}\]
Frequently Asked Questions (FAQ)
- What is creatinine clearance?
- Creatinine clearance is a measure of kidney function, indicating how well kidneys are filtering creatinine from the blood.
- Why is gender important in the calculation?
- Gender affects muscle mass and consequently the production of creatinine, requiring different factors in the formula.
- Is this calculator accurate for children?
- This calculator is not suitable for children; other formulas should be used for pediatric patients.
- Can I use this tool if I have renal impairment?
- Yes, but it's always advised to consult a healthcare professional for personalized assessments.
- How often should I check my creatinine clearance?
- This depends on your health condition; consult your doctor for a tailored advice.